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Genetic and Epigenetic Modifications in Alzheimer’s Disease: Pathophysiology, Biomarkers, and Therapeutics – A Systematic Review

Alzheimer’s disease (AD) is a complex neurodegenerative disorder marked by progressive cognitive decline, memory loss, and behavioral changes. While genetic factors such as mutations in APP, PSEN1, PSEN2, and the APOE ε4 allele have been well established as risk factors, recent research highlights t...

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Principais autores: Dharmendra Kumar Gupta, Arunima Chaudhuri
Formato: Artigo
Idioma:Inglês
Publicado: Wolters Kluwer Medknow Publications 2025-12-01
Series:Medical Journal of Dr. D.Y. Patil Vidyapeeth
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Acceso en liña:https://journals.lww.com/10.4103/mjdrdypu.mjdrdypu_57_25
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