Single cell multiomic landscape reveals gene programs driving lipid droplet heterogeneity in hepatic steatosis

Abstract Alcohol-associated liver disease (ALD) in its earliest form is evidenced as hepatic steatosis which may progress to liver cirrhosis. The mechanisms behind this are poorly understood and therapeutics limited. Liver is a specialized organ exhibiting heterogeneity along the porto-central axis....

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Principais autores:	Tejasav S. Sehrawat, Shawna A. Cooper, Amaia Navarro-Corcuera, Ryan J. Schulze, Mengfei Liu, Usman Yaqoob, Yubin Yeon, Sangwoong Yoon, Yung-Kyun Noh, Chady Meroueh, Joseph C. Ahn, Josepmaria Argemi, Ramon A. Bataller, Mark A. McNiven, Mrunal K. Dehankar, Ying Li, Jeong-Heon Lee, Carol A. Casey, William A. Faubion, Tamas Ordog, Patrick S. Kamath, Douglas A. Simonetto, Harmeet Malhi, Sheng Cao, Vijay H. Shah
Format:	Artigo
Jezik:	Inglês
Izdano:	Nature Portfolio 2026-02-01
Serija:	Scientific Reports
Online dostop:	https://doi.org/10.1038/s41598-026-39913-6
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