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Engineering Adenoviral Vectors with Improved GBM Selectivity

Glioblastoma (GBM) is the most common and aggressive adult brain cancer with an average survival rate of around 15 months in patients receiving standard treatment. Oncolytic adenovirus expressing therapeutic transgenes represent a promising alternative treatment for GBM. Of the many human adenoviral...

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Principais autores: Emily A. Bates, Charlotte Lovatt, Alice R. Plein, James A. Davies, Florian A. Siebzehnrubl, Alan L. Parker
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-04-01
Serier:Viruses
Fag:
brain tumour
oncolytic virus
receptor
therapy
Online adgang:https://www.mdpi.com/1999-4915/15/5/1086
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