Haploinsufficiency of mechanistic target of rapamycin ameliorates bag3 cardiomyopathy in adult zebrafish

The adult zebrafish is an emerging vertebrate model for studying human cardiomyopathies; however, whether the simple zebrafish heart can model different subtypes of cardiomyopathies, such as dilated cardiomyopathy (DCM), remains elusive. Here, we generated and characterized an inherited DCM model in...

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Detalhes bibliográficos

Principais autores:	Yonghe Ding, Alexey V. Dvornikov, Xiao Ma, Hong Zhang, Yong Wang, Matthew Lowerison, Rene R. Packard, Lei Wang, Jun Chen, Yuji Zhang, Tzung Hsiai, Xueying Lin, Xiaolei Xu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	The Company of Biologists 2019-10-01
coleção:	Disease Models & Mechanisms
Assuntos:	dilated cardiomyopathy bcl2-associated athanogene 3 mtor danio rerio
Acesso em linha:	http://dmm.biologists.org/content/12/10/dmm040154
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