PreC and C Regions of Woodchuck Hepatitis Virus Facilitate Persistent Expression of Surface Antigen of Chimeric WHV-HBV Virus in the Hydrodynamic Injection BALB/c Mouse Model

In the hydrodynamic injection (HI) BALB/c mouse model with the overlength viral genome, we have found that woodchuck hepatitis virus (WHV) could persist for a prolonged period of time (up to 45 weeks), while hepatitis B virus (HBV) was mostly cleared at week four. In this study, we constructed a ser...

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Detalhes bibliográficos

Principais autores:	Weimin Wu, Yan Liu, Yong Lin, Danzhen Pan, Dongliang Yang, Mengji Lu, Yang Xu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2017-02-01
coleção:	Viruses
Assuntos:	woodchuck hepatitis virus hepatitis B virus chimeric genome mouse model
Acesso em linha:	http://www.mdpi.com/1999-4915/9/2/35
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