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Explainable drug side effect prediction in central neural system via biologically informed graph neural network

Abstract The early detection of potential side effects (SEs) is a critical yet formidable challenge within the realms of drug development and patient healthcare management. Conventional in-vitro or in-vivo approaches for SE detection are often not feasible to scale during the preclinical phase for n...

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Bibliografiske detaljer
Principais autores: Tongtong Huang, Ko-Hong Lin, Rodrigo Machado-Vieira, Jair C. Soares, Xiaoqian Jiang, Yejin Kim
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2026-03-01
Serier:Translational Psychiatry
Online adgang:https://doi.org/10.1038/s41398-026-03971-1
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