Oxidative stress changes the effectiveness of artemisinin in Plasmodium falciparum

ABSTRACT Malaria parasites have adaptive mechanisms to modulate their intracellular redox status to tolerate the enhanced oxidizing effects created by malaria fever, hemoglobinopathies and other stress conditions, including antimalaria drugs. Emerging artemisinin (ART) resistance in Plasmodium falci...

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Bibliografiske detaljer

Principais autores:	Camilla Valente Pires, Debora Cassandra, Shulin Xu, Benoit Laleu, Jeremy N. Burrows, John H. Adams
Format:	Artigo
Sprog:	Inglês
Udgivet:	American Society for Microbiology 2024-03-01
Serier:	mBio
Fag:	antimalarial agents malaria drug resistance evolution artemisin oxidative stress
Online adgang:	https://journals.asm.org/doi/10.1128/mbio.03169-23
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