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The Co-Localization of NLRP3 and ASC Specks Does Not Automatically Entail NLRP3 Inflammasome Functionality in PDAC Cell Lines

The NLRP3 inflammasome is an important mediator of the host inflammatory response, and downregulation of inflammation is important in cancer treatment. Here, we investigated four different pancreatic ductal adenocarcinoma (PDAC) cell lines, AsPC-1, BxPC-3, CFPAC-1 and Panc-1, with regards to NLRP3 i...

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Bibliografiske detaljer
Principais autores: Heléne Lindholm, Matthew Herring, Maria Faresjö, Johan Haux, Ferenc Szekeres, Katarina Ejeskär
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2024-03-01
Serier:International Journal of Translational Medicine
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Online adgang:https://www.mdpi.com/2673-8937/4/2/13
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