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Mechanism of AGEs-RAGE axis inhibition of ferroptosis in type 2 diabetic colon cancer by regulatory CEACAM1

Abstract Type 2 diabetes mellitus (T2DM) patients with colon cancer have an increased incidence and poor prognosis, which may be closely related to advanced glycation end products (AGEs) and its receptor (RAGE), but the underlying mechanism is still unclear. The aim of this study is to investigate h...

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Autori principali: Kai Liu, Shu Liu, Dong Wang, Tianshu Han, Hong Qiao, Qingxiao Fang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2026-04-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-026-50008-0
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