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Deep Screening for X Chromosome Parent-of-Origin Effects on Neurobehavioral and Neuroanatomical Phenotypes in 47,XXY Klinefelter Syndrome

Background: X chromosome parent of origin (POX) has been proposed as a source of phenotypic variation within sex chromosome aneuploidies such as Klinefelter syndrome (XXY/KS) and between XX and XY individuals. However, previous studies have yielded conflicting results regarding the presence and natu...

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Auteurs principaux: Isabella G. Larsen, Rachel Gore Moses, Bryce A. Seifert, Siyuan Liu, Samuel Li, Andrew J. Oler, Elizabeth Levitis, Lukas Schaffer, Rylee Duncan, Colleen Jodarski, Michael Kamen, Jia Yan, François M. Lalonde, Rajarshi Ghosh, Erin Torres, Liv S. Clasen, Jonathan Blumenthal, Morgan Similuk, Armin Raznahan, Magdalena A. Walkiewicz
Format: Artigo
Langue:Inglês
Publié: Elsevier 2024-11-01
Collection:Biological Psychiatry Global Open Science
Sujets:
47,XXY
Klinefelter syndrome
Neuroanatomy
Neurodevelopment
X chromosome parent of origin
Accès en ligne:http://www.sciencedirect.com/science/article/pii/S2667174324001046
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