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Assessment of morphology, radiopacity gradient and mechanical properties of articular cartilage with contrast-enhanced high-resolution peripheral quantitative computed tomography

IntroductionDegenerative alterations in proteoglycans content and collagen structure compromise the mechanical integrity of articular cartilage and, therefore, its viscoelastic properties. Early detection of these subtle alterations is a prerequisite for enabling intervention with promising treatmen...

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Main Authors: Simone Fantoni, Matteo Berni, Roberta Fognani, Giulia Fraterrigo, Paolo Cardarelli, Fabio Baruffaldi, Massimiliano Baleani
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2026-06-01
Series:Frontiers in Bioengineering and Biotechnology
Subjects:
articular cartilage
contrast agent
indentation
mechanical properties
X-ray imaging
Online Access:https://www.frontiersin.org/articles/10.3389/fbioe.2026.1756342/full
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