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In vitro delayed response to dihydroartemisinin of malaria parasites infecting sickle cell erythocytes

Abstract Background Decreased efficacy of artemisinin-based combination therapy (ACT) for Plasmodium falciparum malaria has been previously reported in patients with sickle cell disease (SCD). The main purpose of this study was to investigate the in vitro susceptibility of isolates to dihydro-artemi...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Albert A. Gnondjui, Offianan A. Toure, Berenger A. Ako, Tossea S. Koui, Stanislas E. Assohoun, Eric A. Gbessi, Landry T. N’Guessan, Karim Tuo, Sylvain Beourou, Serge-Brice Assi, Francis A. Yapo, Ibrahima Sanogo, Ronan Jambou
Format: Artigo
Sprache:Inglês
Veröffentlicht: BMC 2024-01-01
Schriftenreihe:Malaria Journal
Schlagworte:
Sickle cell anemia
Artemisinin combination therapy
Plasmodium falciparum
Anti-malarial drugs
Treatment resistance
In vitro drug monitoring
Online-Zugang:https://doi.org/10.1186/s12936-023-04819-5
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