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Deletion of SM22α disrupts the structure and function of caveolae and T-tubules in cardiomyocytes, contributing to heart failure.

<h4>Aims</h4>Smooth muscle 22-alpha (SM22α) is an actin-binding protein that plays critical roles in mediating polymerization of actin filaments and stretch sensitivity of cytoskeleton in vascular smooth muscle cells (VSMCs). Multiple lines of evidence indicate the existence of SM22α in cardiomyocyt...

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Hlavní autoři: Jun Wu, Wei Wang, Yaomeng Huang, Haochen Wu, Jiabin Wang, Mei Han
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science (PLoS) 2022-01-01
Edice:PLoS ONE
On-line přístup:https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0271578&type=printable
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