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Identification of subgroups and development of prognostic risk models along the glycolysis–cholesterol synthesis axis in lung adenocarcinoma

Abstract Lung cancer is one of the most dangerous malignant tumors affecting human health. Lung adenocarcinoma (LUAD) is the most common subtype of lung cancer. Both glycolytic and cholesterogenic pathways play critical roles in metabolic adaptation to cancer. A dataset of 585 LUAD samples was downl...

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Principais autores: Jiuzhou Jiang, Bao Qian, Yangjie Guo, Zhengfu He
Format: Artigo
Sprog:Inglês
Udgivet: Nature Portfolio 2024-06-01
Serier:Scientific Reports
Fag:
Glycolysis
Cholesterol
XGBoost
SHAP
Online adgang:https://doi.org/10.1038/s41598-024-64602-7
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