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Stimulation of the rat subthalamic nucleus is neuroprotective following significant nigral dopamine neuron loss

Deep brain stimulation of the subthalamic nucleus (STN-DBS) is efficacious in treating the motor symptoms of Parkinson's disease (PD). However, the impact of STN-DBS on the progression of PD is unknown. Previous preclinical studies have demonstrated that STN-DBS can attenuate the degeneration of a r...

Deskribapen osoa

Gorde:
Egile Nagusiak: A.L. Spieles-Engemann, M.M. Behbehani, T.J. Collier, S.L. Wohlgenant, K. Steece-Collier, K. Paumier, B.F. Daley, S. Gombash, L. Madhavan, G.T. Mandybur, J.W. Lipton, B.T. Terpstra, C.E. Sortwell
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Elsevier 2010-07-01
Saila:Neurobiology of Disease
Gaiak:
Deep brain stimulation
Subthalamic nucleus
Parkinson's disease
Neuroprotection
6-hydroxydopamine
Stereology
Sarrera elektronikoa:http://www.sciencedirect.com/science/article/pii/S0969996110000707
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