High Endothelial Venules: A Vascular Perspective on Tertiary Lymphoid Structures in Cancer

High endothelial venules (HEVs) are specialized postcapillary venules composed of cuboidal blood endothelial cells that express high levels of sulfated sialomucins to bind L-Selectin/CD62L on lymphocytes, thereby facilitating their transmigration from the blood into the lymph nodes (LN) and other se...

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Auteurs principaux:	Gerlanda Vella, Sophie Guelfi, Gabriele Bergers
Format:	Artigo
Langue:	Inglês
Publié:	Frontiers Media S.A. 2021-08-01
Collection:	Frontiers in Immunology
Sujets:	high endothelial venules tertiary lymphoid structures tumor endothelial cells tumor immunity immunotherapy lymphotoxin beta receptor
Accès en ligne:	https://www.frontiersin.org/articles/10.3389/fimmu.2021.736670/full
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