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Sorcin regulates alveolarization and airway tissue remodeling during lung morphogenesis

Abstract Sorcin, a key calcium-sensing protein, regulates calcium concentration within the endoplasmic reticulum (ER), promoting apoptosis resistance and ER stress. It also modulates downstream signaling pathways of the epidermal growth factor receptor (EGFR), influencing cellular migration and inva...

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Kaydedildi:
Asıl Yazarlar: Claudia Tito, Luciana De Angelis, Alessia Iaiza, Annalisa Pia Abbinantefina, Anna Benedetti, Gilla Mazzanti, Vincenzo Petrozza, Mattia Lauriola, Luca Tamagnone, Andrea Ilari, Silvia Masciarelli, Gianni Colotti, Francesco Fazi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Springer 2025-10-01
Seri Bilgileri:Cellular and Molecular Life Sciences
Konular:
Lung development
Sorcin KO
Alveolarization
Branching morphogenesis
Airway remodeling
Online Erişim:https://doi.org/10.1007/s00018-025-05870-y
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