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N-terminal acetylation controls multiple functional aspects of the influenza A virus ribonuclease PA-X

ABSTRACT To counteract host antiviral responses, influenza A virus triggers a global reduction of cellular gene expression, a process termed “host shutoff.” A key effector of influenza A virus host shutoff is the viral endoribonuclease PA-X, which degrades host mRNAs. While many of the molecular det...

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Bibliografische gegevens
Hoofdauteurs: Raecliffe E. Daly, Cynthia Y. Feng, Charles R. Hesser, Idalia Myasnikov, Marta Maria Gaglia
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology 2026-02-01
Reeks:Journal of Virology
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Online toegang:https://journals.asm.org/doi/10.1128/jvi.01999-25
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