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Binase Immobilized on Halloysite Nanotubes Exerts Enhanced Cytotoxicity toward Human Colon Adenocarcinoma Cells

Many ribonucleases (RNases) are considered as promising tools for antitumor therapy because of their selective cytotoxicity toward cancer cells. Binase, the RNase from Bacillus pumilus, triggers apoptotic response in cancer cells expressing RAS oncogene which is mutated in a large percentage of prev...

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Principais autores: Vera Khodzhaeva, Anna Makeeva, Vera Ulyanova, Pavel Zelenikhin, Vladimir Evtugyn, Martin Hardt, Elvira Rozhina, Yuri Lvov, Rawil Fakhrullin, Olga Ilinskaya
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2017-09-01
Serier:Frontiers in Pharmacology
Fag:
Bacillus pumilus
RNase
binase
halloysite
nanotubes
colon adenocarcinoma
Online adgang:http://journal.frontiersin.org/article/10.3389/fphar.2017.00631/full
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