Structural Basis for Vascular Endothelial Growth Factor Receptor Activation and Implications for Disease Therapy

Vascular endothelial growth factors (VEGFs) bind to membrane receptors on a wide variety of cells to regulate diverse biological responses. The VEGF-A family member promotes vasculogenesis and angiogenesis, processes which are essential for vascular development and physiology. As angiogenesis can be...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Faheem Shaik, Gary A. Cuthbert, Shervanthi Homer-Vanniasinkam, Stephen P. Muench, Sreenivasan Ponnambalam, Michael A. Harrison
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2020-12-01
Schriftenreihe:	Biomolecules
Schlagworte:	angiogenesis VEGFR receptor tyrosine kinase signal transduction cancer bevacizumab
Online-Zugang:	https://www.mdpi.com/2218-273X/10/12/1673
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