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Ion channel Piezo1 activation promotes aerobic glycolysis in macrophages

Altered microenvironmental stiffness is a hallmark of inflammation. It is sensed by the mechanically activated cation channel Piezo1 in macrophages to induce subsequent immune responses. However, the mechanism by which the mechanosensitive signals shape the metabolic status of macrophages and tune i...

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Autors principals: Shaoqiu Leng, Xiaoyu Zhang, Shuwen Wang, Jing Qin, Qiang Liu, Anli Liu, Zi Sheng, Qi Feng, Xiang Hu, Jun Peng
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2022-09-01
Col·lecció:Frontiers in Immunology
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Accés en línia:https://www.frontiersin.org/articles/10.3389/fimmu.2022.976482/full
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