Next-Generation Genome-Scale Metabolic Modeling through Integration of Regulatory Mechanisms

Genome-scale metabolic models (GEMs) are powerful tools for understanding metabolism from a systems-level perspective. However, GEMs in their most basic form fail to account for cellular regulation. A diverse set of mechanisms regulate cellular metabolism, enabling organisms to respond to a wide ran...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Carolina H. Chung, Da-Wei Lin, Alec Eames, Sriram Chandrasekaran
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2021-09-01
Schriftenreihe:	Metabolites
Schlagworte:	metabolic regulation metabolic networks constraint-based modeling systems biology genome-scale network models
Online-Zugang:	https://www.mdpi.com/2218-1989/11/9/606
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