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Real-time tracking of stem cell viability, proliferation, and differentiation with autonomous bioluminescence imaging

Abstract Background Luminescent reporter proteins are vital tools for visualizing cells and cellular activity. Among the current toolbox of bioluminescent systems, only bacterial luciferase has genetically defined luciferase and luciferin synthesis pathways that are functional at the mammalian cell...

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Principais autores: Michael Conway, Tingting Xu, Andrew Kirkpatrick, Steven Ripp, Gary Sayler, Dan Close
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2020-07-01
Serier:BMC Biology
Fag:
Autobioluminescence
Bacterial luciferase
Bioimaging
Lux
Stem cells
iPSC
Online adgang:http://link.springer.com/article/10.1186/s12915-020-00815-2
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