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Musashi2 is required for the self-renewal and pluripotency of embryonic stem cells.

Recent studies have shown that the RNA binding protein Musashi 2 (Msi2) plays important roles during development. Msi2 has also been shown to be elevated in several leukemias and its elevated expression has been linked with poorer prognosis in these cancers. Additionally, in embryonic stem cells (ES...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Erin L Wuebben, Sunil K Mallanna, Jesse L Cox, Angie Rizzino
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science (PLoS) 2012-01-01
Schriftenreihe:PLoS ONE
Online-Zugang:http://europepmc.org/articles/PMC3319613?pdf=render
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