Early-stage idiopathic Parkinson’s disease is associated with reduced circular RNA expression

Abstract Neurodegeneration in Parkinson’s disease (PD) precedes diagnosis by years. Early neurodegeneration may be reflected in RNA levels and measurable as a biomarker. Here, we present the largest quantification of whole blood linear and circular RNAs (circRNA) in early-stage idiopathic PD, using...

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Hlavní autoři:	Benjamin J. Whittle, Osagie G. Izuogu, Hannah Lowes, Dasha Deen, Angela Pyle, Jon Coxhead, Rachael A. Lawson, Alison J. Yarnall, Michael S. Jackson, Mauro Santibanez-Koref, Gavin Hudson
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Nature Portfolio 2024-01-01
Edice:	npj Parkinson's Disease
On-line přístup:	https://doi.org/10.1038/s41531-024-00636-y
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