Evaluation of pre-analytical factors affecting plasma DNA analysis

Abstract Pre-analytical factors can significantly affect circulating cell-free DNA (cfDNA) analysis. However, there are few robust methods to rapidly assess sample quality and the impact of pre-analytical processing. To address this gap and to evaluate effects of DNA extraction methods and blood col...

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Principais autores:	Havell Markus, Tania Contente-Cuomo, Maria Farooq, Winnie S. Liang, Mitesh J. Borad, Shivan Sivakumar, Simon Gollins, Nhan L. Tran, Harshil D. Dhruv, Michael E. Berens, Alan Bryce, Aleksandar Sekulic, Antoni Ribas, Jeffrey M. Trent, Patricia M. LoRusso, Muhammed Murtaza
格式:	Artigo
語言:	Inglês
出版:	Nature Portfolio 2018-05-01
叢編:	Scientific Reports
在線閱讀:	https://doi.org/10.1038/s41598-018-25810-0
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