Protective effects of calcyclin-binding protein against pulmonary vascular remodeling in flow-associated pulmonary arterial hypertension

Abstract Background Pulmonary arterial hypertension associated with congenital heart disease (CHD-PAH) is recognized as a cancer-like disease with a proliferative and pro-migratory phenotype in pulmonary artery smooth muscle cells (PASMCs). Calcyclin-binding protein/Siah-1-interacting protein (CacyB...

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Detalhes bibliográficos

Principais autores:	Jingjing Zhou, FuRong Li, Yicheng Yang
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2022-08-01
coleção:	Respiratory Research
Assuntos:	Congenital heart disease Pulmonary arterial hypertension Pulmonary artery smooth muscle cells Calcyclin-binding protein/Siah-1-interacting protein Pulmonary vascular remodeling
Acesso em linha:	https://doi.org/10.1186/s12931-022-02137-z
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