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WNK4 is the major WNK positively regulating NCC in the mouse kidney

By analysing the pathogenesis of a hereditary hypertensive disease, PHAII (pseudohypoaldosteronism type II), we previously discovered that WNK (with-no-lysine kinase)–OSR1/SPAK (oxidative stress-responsive 1/Ste20-like proline/alanine-rich kinase) cascade regulates NCC (Na–Cl co-transporter) in the...

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Principais autores: Daiei Takahashi, Takayasu Mori, Naohiro Nomura, Muhammad Zakir Hossain Khan, Yuya Araki, Moko Zeniya, Eisei Sohara, Tatemitsu Rai, Sei Sasaki, Shinichi Uchida
Format: Artigo
Jezik:Inglês
Izdano: Portland Press 2014-05-01
Serija:Bioscience Reports
Teme:
angiotensin II
distal convoluted tubule
hypertension
kidney
Na–Cl co-transporter
with-no-lysine kinase (WNK)
Online dostop:http://www.bioscirep.org/bsr/034/e107/bsr034e107.htm
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