Individual MHCI restricted T-cell receptors are characterized by a unique peptide recognition signature

Effective immunity requires that a limited TCR repertoire is able to recognize a vast number of foreign peptide-MHCI. This challenge is overcome by the ability of individual TCRs to recognize large numbers of peptides. Recently, it was demonstrated that MHCI-restricted TCRs can recognize up to 10^6...

Deskribapen osoa

Xehetasun bibliografikoak

Egile nagusia:	Linda eWooldridge
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2013-07-01
Saila:	Frontiers in Immunology
Gaiak:	Autoimmunity Vaccination alloreactivity MHCI peptide length CD8 T-cell immunity T-cell cross-reactivity
Sarrera elektronikoa:	http://journal.frontiersin.org/Journal/10.3389/fimmu.2013.00199/full
Etiketak:	Etiketa erantsi Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!