Reduced platelet count in mice protects against glucose intolerance and beta cell loss during a long-term high-fat diet

IntroductionPlatelets promote hemostasis and modulate different inflammatory and immunological processes. Recently, it was reported that platelets interact with pancreatic beta cells to increase insulin secretion. Inflammatory conditions and a lack of sufficient insulin secretion drive the pathogene...

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Principais autores:	Niklas Burkhard, Johannes Hoch, Shanshan Zhang, Muataz Ali Hamad, Nicolas Schommer, Carolin Mogler, Daniela Stallmann, Pierre Mangin, Krystin Krauel, Daniel Duerschmied, Nancy Schanze
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2026-07-01
coleção:	Frontiers in Immunology
Assuntos:	diabetes glucose tolerance insulin secretion obesity pancreatic beta cells platelets
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fimmu.2026.1854992/full
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