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SOX2OT variant 7 contributes to the synergistic interaction between EGCG and Doxorubicin to kill osteosarcoma via autophagy and stemness inhibition

Abstract Background Doxorubicin is the preferred chemotherapeuticdrug for osteosarcoma treatment of which clinical efficacy is limited because of its chemo-resistance and cardiac toxicity. It is necessary to develop the combination regimen with complementary molecular mechanisms to reduce the side e...

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Autors principals: Wanchun Wang, Ding Chen, Kewei Zhu
Format: Artigo
Idioma:Inglês
Publicat: BMC 2018-02-01
Col·lecció:Journal of Experimental & Clinical Cancer Research
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Accés en línia:http://link.springer.com/article/10.1186/s13046-018-0689-3
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