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Evolution of type 2 vaccine derived poliovirus lineages. Evidence for codon-specific positive selection at three distinct locations on capsid wall.

Partial sequences of 110 type 2 poliovirus strains isolated from sewage in Slovakia in 2003-2005, and most probably originating from a single dose of oral poliovirus vaccine, were subjected to a detailed genetic analysis. Evolutionary patterns of these vaccine derived poliovirus strains (SVK-aVDPV2)...

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Detalhes bibliográficos
Principais autores: Tapani Hovi, Carita Savolainen-Kopra, Teemu Smura, Soile Blomqvist, Haider Al-Hello, Merja Roivainen
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science (PLoS) 2013-01-01
coleção:PLoS ONE
Acesso em linha:http://europepmc.org/articles/PMC3696017?pdf=render
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