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20(S)-Ginsenoside Rh2 displays efficacy against T-cell acute lymphoblastic leukemia through the PI3K/Akt/mTOR signal pathway

Background: T-cell acute lymphoblastic leukemia (T-ALL) is a kind of aggressive hematological cancer, and the PI3K/Akt/mTOR signaling pathway is activated in most patients with T-ALL and responsible for poor prognosis. 20(S)-Ginsenoside Rh2 (20(S)-GRh2) is a major active compound extracted from gins...

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Principais autores: Ting Xia, Jin Zhang, Chuanxin Zhou, Yu Li, Wenhui Duan, Bo Zhang, Min Wang, Jianpei Fang
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2020-09-01
סדרה:Journal of Ginseng Research
נושאים:
Apoptosis
Autophagy
Ginsenoside Rh2
PI3K/Akt/mTOR
T-cell acute lymphoblastic leukemia
גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S1226845319301137
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