A bile acid–GPBAR1 network supports anti-inflammatory and anti-fibrotic benefits of probiotics in colitis

Intestinal fibrosis is a severe complication of Crohn's disease for which therapy remains suboptimal. Probiotics are widely used in the treatment of intestinal inflammation, but all major guidelines do not recommend in favor of their use, with the exception of an 8-strains bacterial formula, which i...

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Autors principals:	Michele Biagioli, Cristina Di Giorgio, Silvia Marchianò, Benedetta Sensini, Ginevra Urbani, Eleonora Giannelli, Ginevra Lachi, Carmen Massa, Maria Rosaria Sette, Francesca Paniconi, Elva Morretta, Maria Chiara Monti, Angela Zampella, Eleonora Distrutti, Stefano Fiorucci
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2026-12-01
Col·lecció:	Gut Microbes
Matèries:	Secondary bile acids GPBAR1 intestinal fibrosis IBD probiotic 3-oxo-DCA
Accés en línia:	https://www.tandfonline.com/doi/10.1080/19490976.2026.2645125
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