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Cisplatin induced Mitochondrial DNA damage in dorsal root ganglion neurons

Cisplatin is a platinum-based chemotherapeutic agent that induces peripheral neuropathy in 30% of patients. Peripheral neuropathy is the dose limiting side effect, which has no preventative therapy. We have previously shown that cisplatin induces apoptosis in dorsal root ganglion (DRG) sensory neuro...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Jewel L. Podratz, Andrew M. Knight, Lauren E. Ta, Nathan P. Staff, Jennifer M. Gass, Konstantin Genelin, Alexander Schlattau, Liselle Lathroum, Anthony J. Windebank
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2011-03-01
Schriftenreihe:Neurobiology of Disease
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Online-Zugang:http://www.sciencedirect.com/science/article/pii/S096999611000392X
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