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Determinants of the cytosolic turnover of mitochondrial intermembrane space proteins

Abstract Background The proteome of mitochondria comprises mostly proteins that originate as precursors in the cytosol. Before import into the organelle, such proteins are exposed to cytosolic quality control mechanisms. Multiple lines of evidence indicate a significant contribution of the major cyt...

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Principais autores: Lukasz Kowalski, Piotr Bragoszewski, Anton Khmelinskii, Edyta Glow, Michael Knop, Agnieszka Chacinska
Formato: Artigo
Idioma:Inglês
Publicado: BMC 2018-06-01
Series:BMC Biology
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Acceso en liña:http://link.springer.com/article/10.1186/s12915-018-0536-1
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