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Reduced immunomodulatory metabolite concentrations in peri-transplant fecal samples from heart allograft recipients

BackgroundEmerging evidence is revealing the impact of the gut microbiome on hematopoietic and solid organ transplantation. Prior studies postulate that this influence is mediated by bioactive metabolites produced by gut-dwelling commensal bacteria. However, gut microbial metabolite production has n...

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Автори: Mark Dela Cruz, Huaiying Lin, Jiho Han, Emerald Adler, Jaye Boissiere, Maryam Khalid, Ashley Sidebottom, Anitha Sundararajan, Christopher Lehmann, Angelica Moran, Matthew Odenwald, Matthew Stutz, Gene Kim, Sean Pinney, Valluvan Jeevanandam, Maria-Luisa Alegre, Eric Pamer, Ann B. Nguyen
Формат: Artigo
Мова:Inglês
Опубліковано: Frontiers Media S.A. 2023-07-01
Серія:Frontiers in Transplantation
Предмети:
gut microbiome
heart transplant
gut microbial metabolites
short chain fatty acids
secondary bile acid
gut microbial diversity
Онлайн доступ:https://www.frontiersin.org/articles/10.3389/frtra.2023.1182534/full
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