Dose-dependent changes in global brain activity and functional connectivity following exposure to psilocybin: a BOLD MRI study in awake rats

Psilocybin is a hallucinogen with complex neurobiological and behavioral effects. This is the first study to use MRI to follow functional changes in brain activity in response to different doses of psilocybin in fully awake, drug naive rats. We hypothesized that psilocybin would show a dose-dependen...

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Váldodahkkit:	Evan Fuini, Arnold Chang, Richard J. Ortiz, Taufiq Nasseef, Josh Edwards, Marc Latta, Elias Gonzalez, Taylor J. Woodward, Bryce Axe, Ashwath Maheswari, Noah Cavallaro, Heather B. Bradshaw, Praveen P. Kulkarni, Craig F. Ferris
Materiálatiipa:	Artigo
Giella:	Inglês
Almmustuhtton:	Frontiers Media S.A. 2025-05-01
Ráidu:	Frontiers in Neuroscience
Fáttát:	psilocin cerebellar nuclei BOLD resting state functional connectivity 5-HT2A receptor hyperconnectivity
Liŋkkat:	https://www.frontiersin.org/articles/10.3389/fnins.2025.1554049/full
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