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OTULIN deficiency: focus on innate immune system impairment

OTULIN deficiency is a complex disease characterized by a wide range of clinical manifestations, including skin rash, joint welling, lipodystrophy to pulmonary abscess, and sepsis shock. This disease is mechanistically linked to mutations in the OTULIN gene, resulting in an immune disorder that comp...

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Hlavní autoři: Bo Dou, Gang Jiang, Wang Peng, Chentao Liu
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2024-05-01
Edice:Frontiers in Immunology
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On-line přístup:https://www.frontiersin.org/articles/10.3389/fimmu.2024.1371564/full
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