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A proteogenomic signature of age-related macular degeneration in blood

Age related macular degeneration is a common cause of visual impairment in the elderly, but the etiology is not fully understood. Here, the authors use genetic data, serum proteomics, and AMD phenotypic data from a large Icelandic cohort to discover proteins altered in, causally related to AMD or si...

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主要な著者: Valur Emilsson, Elias F. Gudmundsson, Thorarinn Jonmundsson, Brynjolfur G. Jonsson, Michael Twarog, Valborg Gudmundsdottir, Zhiguang Li, Nancy Finkel, Stephen Poor, Xin Liu, Robert Esterberg, Yiyun Zhang, Sandra Jose, Chia-Ling Huang, Sha-Mei Liao, Joseph Loureiro, Qin Zhang, Cynthia L. Grosskreutz, Andrew A. Nguyen, Qian Huang, Barrett Leehy, Rebecca Pitts, Thor Aspelund, John R. Lamb, Fridbert Jonasson, Lenore J. Launer, Mary Frances Cotch, Lori L. Jennings, Vilmundur Gudnason, Tony E. Walshe
フォーマット: Artigo
言語:Inglês
出版事項: Nature Portfolio 2022-06-01
シリーズ:Nature Communications
オンライン・アクセス:https://doi.org/10.1038/s41467-022-31085-x
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