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Novel Regulatory Factors and Small-Molecule Inhibitors of FGFR4 in Cancer

Fibroblast growth factor receptor 4 (FGFR4) is a tyrosine kinase receptor that is a member of the fibroblast growth factor receptor family and is stimulated by highly regulated ligand binding. Excessive expression of the receptor and its ligand, especially FGF19, occurs in many types of cancer. Abno...

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Principais autores: Yanan Liu, Canwei Wang, Jifa Li, Jiandong Zhu, Chengguang Zhao, Huanhai Xu
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2021-04-01
coleção:Frontiers in Pharmacology
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Acesso em linha:https://www.frontiersin.org/articles/10.3389/fphar.2021.633453/full
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