Mutational burden and potential oligogenic model of TBX6‐mediated genes in congenital scoliosis

Abstract Background Congenital scoliosis (CS) is a spinal deformity due to vertebral malformations. Although insufficiency of TBX6 dosage contributes to a substantial proportion of CS, the molecular etiology for the majority of CS remains largely unknown. TBX6‐mediated genes involved in the process...

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Detalhes bibliográficos

Principais autores:	Yang Yang, Sen Zhao, Yuanqiang Zhang, Shengru Wang, Jiashen Shao, Bowen Liu, Yaqi Li, Zihui Yan, Yuchen Niu, Xiaoxin Li, Lianlei Wang, Yongyu Ye, Xisheng Weng, Zhihong Wu, Deciphering Disorders Involving Scoliosis and COmorbidities (DISCO) study, Jianguo Zhang, Nan Wu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Wiley 2020-10-01
coleção:	Molecular Genetics & Genomic Medicine
Assuntos:	congenital scoliosis exome sequencing mutational burden TBX6‐mediated genes
Acesso em linha:	https://doi.org/10.1002/mgg3.1453
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