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Mutations in LRRC50 predispose zebrafish and humans to seminomas.

Seminoma is a subclass of human testicular germ cell tumors (TGCT), the most frequently observed cancer in young men with a rising incidence. Here we describe the identification of a novel gene predisposing specifically to seminoma formation in a vertebrate model organism. Zebrafish carrying a heter...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Sander G Basten, Erica E Davis, Ad J M Gillis, Ellen van Rooijen, Hans Stoop, Nikolina Babala, Ive Logister, Zachary G Heath, Trudy N Jonges, Nicholas Katsanis, Emile E Voest, Freek J van Eeden, Rene H Medema, René F Ketting, Stefan Schulte-Merker, Leendert H J Looijenga, Rachel H Giles
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: Public Library of Science (PLoS) 2013-04-01
Цуврал:PLoS Genetics
Онлайн хандалт:http://europepmc.org/articles/PMC3627517?pdf=render
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