Tissue-Specific Mitochondrial Decoding of Cytoplasmic Ca2+ Signals Is Controlled by the Stoichiometry of MICU1/2 and MCU

Mitochondrial Ca2+ uptake through the Ca2+ uniporter supports cell functions, including oxidative metabolism, while meeting tissue-specific calcium signaling patterns and energy needs. The molecular mechanisms underlying tissue-specific control of the uniporter are unknown. Here, we investigated a p...

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Bibliografiske detaljer

Principais autores:	Melanie Paillard, György Csordás, Gergö Szanda, Tünde Golenár, Valentina Debattisti, Adam Bartok, Nadan Wang, Cynthia Moffat, Erin L. Seifert, András Spät, György Hajnóczky
Format:	Artigo
Sprog:	Inglês
Udgivet:	Elsevier 2017-03-01
Serier:	Cell Reports
Fag:	calcium uniporter calcium oscillations signal decoding
Online adgang:	http://www.sciencedirect.com/science/article/pii/S2211124717302139
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