Mitochondrial ferroptosis in cardiovascular diseases: Mechanisms, biomarkers, and therapeutic opportunities — A narrative review

Background: cardiovascular diseases (CVDs) are propelled by mitochondrial ferroptosis, an iron-dependent cell death involving ROS-driven lipid peroxidation, with mitochondria as key regulators via dynamics, iron flux, and antioxidant defences like GPX4/NRF2. Objectives: To delineate mitochondrial me...

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Detalhes bibliográficos

Principais autores:	Siana Veedal Sequeira, Gayathri M Rao, Maneesh Rai, Sheetal Ullal, Sharada Rai, Aradhana Marathe, Chaithra GV, Narasimha Pai D, Ajeetkumar Patil
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Elsevier 2026-06-01
coleção:	Advances in Redox Research
Assuntos:	Ferroptosis Mitochondria Cardiomyocyte Myocardial infarction Iron metabolism Lipid peroxidation
Acesso em linha:	http://www.sciencedirect.com/science/article/pii/S2667137926000196
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