Single-cell spatial transcriptomics uncovers niches that govern response to PD-1/PD-L1 blockade in cutaneous squamous cell carcinoma

Background Neoadjuvant PD-1/PD-L1 blockade yields robust efficacy in advanced cutaneous squamous cell carcinoma (cSCC), yet many patients fail to achieve a complete or major pathologic response. The reasons why some patients experience response but others do not are unclear.Methods We profiled cSCC...

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Номзүйн дэлгэрэнгүй

Үндсэн зохиолчид:	John B Sunwoo, Maxwell Y Lee, Sabrina Zdravkovic, Ivan Stepanek, Alistaire R Sherman, Luis Martinez Ramirez, Mobeen Rahman, June Ho Shin, Alexander Dimitrios Colevas, Vasu Divi
Формат:	Artigo
Хэл сонгох:	Inglês
Хэвлэсэн:	BMJ Publishing Group 2026-01-01
Цуврал:	Journal for ImmunoTherapy of Cancer
Онлайн хандалт:	https://jitc.bmj.com/content/14/1/e014067.full
Шошгууд:	Шошго нэмэх Шошго байхгүй, Энэхүү баримтыг шошголох эхний хүн болох!