The cGAS-STING pathway in atherosclerosis

Atherosclerosis (AS), a chronic inflammatory disease, remains a leading contributor to cardiovascular morbidity and mortality. Recent studies highlight the critical role of the cGAS-STING pathway—a key innate immune signaling cascade—in driving AS progression. This pathway is activated by cytoplasmi...

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Bibliografiske detaljer

Principais autores:	Si-yu Wang, Yu-shan Chen, Bo-yuan Jin, Ahmad Bilal
Format:	Artigo
Sprog:	Inglês
Udgivet:	Frontiers Media S.A. 2025-04-01
Serier:	Frontiers in Cardiovascular Medicine
Fag:	atherosclerosis cGAS-STING pathway risk factors therapeutic potential cGAS inhibitors STING inhibitors
Online adgang:	https://www.frontiersin.org/articles/10.3389/fcvm.2025.1550930/full
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