Ergosta-7,9(11),22-trien-3β-ol Attenuates Inflammatory Responses via Inhibiting MAPK/AP-1 Induced IL-6/JAK/STAT Pathways and Activating Nrf2/HO-1 Signaling in LPS-Stimulated Macrophage-like Cells

Chronic inflammation induces autoimmune disorders and chronic diseases. Several natural products activate nuclear factor erythroid 2-related factor 2 (Nrf2) signaling, attenuating inflammatory responses. Ergosta-7,9(11),22-trien-3β-ol (EK100) isolated from <i>Cordyceps militaris</i> showed anti-infl...

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Autors principals:	Yi-Ping Huang, Dar-Ren Chen, Wen-Jen Lin, Yu-Hsien Lin, Jiann-Yeu Chen, Yueh-Hsiung Kuo, Jing-Gung Chung, Te-Chun Hsia, Wen-Tsong Hsieh
Format:	Artigo
Idioma:	Inglês
Publicat:	MDPI AG 2021-09-01
Col·lecció:	Antioxidants
Matèries:	Ergosta-7,9(11),22-trien-3β-ol (EK100) <i>Cordyceps militaris</i> anti-inflammatory response MAPK/AP-1 signaling pathways IL-6/JAK/STAT signaling pathways Nrf2/ HO-1 signaling pathway
Accés en línia:	https://www.mdpi.com/2076-3921/10/9/1430
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