Development and validation of next-generation sequencing-based clinical test for triazole resistance prediction in Aspergillus fumigatus

ABSTRACT The rising rates of triazole drug resistance in Aspergillus fumigatus have placed greater reliance on antifungal susceptibility testing (AFST) to guide therapeutic management, particularly in medically complicated patients. Current methods, however, utilize conventional phenotypic assays th...

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Principais autores:	J. R. Caldera, Ashley Dayo, Nathan Wiederhold, Shangxin Yang
Formato:	Artigo
Idioma:	Inglês
Publicado:	American Society for Microbiology 2025-08-01
Series:	Journal of Clinical Microbiology
Assuntos:	Aspergillus fumigatus azole resistance whole-genome sequencing genotyping antifungal resistance next-generation sequencing
Acceso en liña:	https://journals.asm.org/doi/10.1128/jcm.00291-25
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