Mutant IDH and non-mutant chondrosarcomas display distinct cellular metabolomes
Abstract Background Majority of chondrosarcomas are associated with a number of genetic alterations, including somatic mutations in isocitrate dehydrogenase 1 (IDH1) and IDH2 genes, but the downstream effects of these mutated enzymes on cellular metabolism and tumor energetics are unknown. As IDH mu...
Gespeichert in:
| Hauptverfasser: | , , , , , , , , |
|---|---|
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
BMC
2021-03-01
|
| Schriftenreihe: | Cancer & Metabolism |
| Schlagworte: | |
| Online-Zugang: | https://doi.org/10.1186/s40170-021-00247-8 |
| Tags: |
Keine Tags, Fügen Sie das erste Tag hinzu!
|